Since its description and introduction to clinical practice, serum protein electrophoresis has been useful as a first-line test for serum albumin and globulins and to identify monoclonal gammopathies, agammaglobulinemia, polyclonal production of immunoglobulins, and increase/decrease of other proteins. The electrophoresis drawing provided by laboratory shows five main protein fractions of serum. Nevertheless, it is sometimes difficult for students, residents, nurses, and non-specialized…