donnelly centre building

Advancing discovery, medicine and health

Donnelly Centre is a global research hub where scientists from diverse fields explore the power of genomic technology to advance discovery, medicine and health.
map of genetic interactions
Michael Costanzo
A global map of genetic interactions showing how thousands of genes work together to sustain cellular fitness.
Jul 18, 2024
A new study from Toronto General Hospital Research Institute (TGHRI) and McEwen Stem Cell Institute (McEwen) has uncovered a novel method to model the involvement of yolk sac macrophages—precursors to immune cells during embryonic development—in human heart development.
Jul 15, 2024
A research team at UHN’s Donald K. Johnson Eye Institute, in collaboration with the Institute of Biomedical Engineering at the University of Toronto (U of T), has discovered that transplanted retinal cells can share essential materials with host cells in the lab, offering a promising avenue for delivering therapies directly to damaged areas of the eye.
Jul 10, 2024
Researchers at the University of Toronto have made strides in heart disease research by incorporating primitive macrophages—a crucial immune cell—into heart-on-a-chip technology. This innovative approach promises to enhance the functionality and stability of engineered heart tissues, potentially transforming drug testing and disease modeling.