09/30/2020
Opinion
Edgeworth and colleagues discuss their transition to a COVID-19 diagnostics and translational research group. They focus on how clinicians, clinical academics, research and healthcare scientists as well as research nurses came together on the ground to highlight the successes and opportunities alongside the challenges and obstacles that may be common themes.
Image credit: PIXNIO
Current Issue September 2020
10/09/2020
Review
Kinsella et al outline key components of an adequate research response to novel viral outbreaks using the example of SARS-CoV-2. They highlight the exceptional recent progress made in fundamental science, resulting in the fastest scientific response to a major infectious disease outbreak or pandemic.
Image credit: ppat.1008902
10/15/2020
Pearls
In this Pearls article, Sam S. Cassidy and colleagues call upon industry, policy makers, and healthcare agencies to recognise that (1) research must address the potential impact of antimicrobial surfaces on AMR before they are employed; (2) there is a need for stewardship of antimicrobial surfaces intended for the healthcare setting; and (3) the broader exploitation of antimicrobial surfaces must not be undertaken lightly and requires oversight.
Image credit: ppat.1008880
10/02/2020
Research Article
Li-hui He and colleagues demonstrate the crucial role of CfaA-CfaE in CFA/I fimbriae production, providing guidance for further development of novel agents targeting CFA/I fimbriae and against enterotoxigenic Escherichia coli infection.
Image credit: ppat.1008848
10/02/2020
Research Article
Crisford & Calahorro et al identify key components of the serotonin signalling pathway in Globodera pallida and show that chemicals that target these sites also inhibit ability to invade the host plant, providing insight into new targets for crop protection.
Image credit: Florida Division of Plant Industry
10/08/2020
Research Article
Puhach et al study the viral m139 gene, which is important for virus replication in macrophages and endothelial cells and for dissemination in the mouse, and identify m139 as a new viral DDX3 inhibitor, which curtails the production of interferon by macrophages.
Image credit: ppat.1008546
10/05/2020
Research Article
Hakimi and colleagues provide new insights into the host cell modifications by Babesia bovis and their pathogenicity.
Image credit: ppat.1008917
10/07/2020
Research Article
Ohno et al provide insights into how gut microbes control colitis via the complement system.
Image credit: ppat.1008928
10/01/2020
Research Article
Mei at al uncover a novel strategy deployed by geminiviruses to counter anti-viral DNA methylation.
Image credit: ppat.1008829
09/25/2020
Research Article
Gang Yu and colleagues find a bacterial effector protein which prevents MAPK-mediated phosphorylation of SGT1 to suppress plant immunity.
Image credit: ppat.1008933
A Pearls article by Ludington and Ja
Margarida Sa Ribero, Nolwenn Jouvenet, Marlène Dreux & Sébastien Nisole
Sandra Silva-Arrieta, Philip J. R. Goulder & Christian Brander
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