Jounce Therapeutics, Inc.
Biotechnology Research
Cambridge, MA 12,630 followers
Daring to create a world immune to cancer.
About us
Jounce Therapeutics, Inc. is a clinical-stage immunotherapy company dedicated to transforming the treatment of cancer by developing therapies that enable the immune system to attack tumors and aiming to provide long-lasting benefits to patients through a biomarker-driven approach. Jounce currently has multiple development stage programs ongoing while simultaneously advancing additional early-stage assets from its robust discovery engine based on its Translational Science Platform. Jounce’s highest priority program, JTX-8064, is a LILRB2 (ILT4) receptor antagonist shown to reprogram immune-suppressive tumor associated macrophages to an anti-tumor state in preclinical studies. A Phase 1 clinical trial, named INNATE, for JTX-8064 as a monotherapy and in combination with JTX-4014, Jounce’s internal PD-1 inhibitor, or pembrolizumab is currently enrolling patients with advanced solid tumors. Jounce’s most advanced product candidate, vopratelimab, is a monoclonal antibody that binds to and activates ICOS, and is currently being studied in the SELECT Phase 2 trial. JTX-4014 is a PD-1 inhibitor intended for combination use in the INNATE and SELECT trials and with Jounce’s broader pipeline. Additionally, Jounce exclusively licensed worldwide rights to JTX-1811, a monoclonal antibody targeting CCR8 and designed to selectively deplete T regulatory cells in the tumor microenvironment, to Gilead Sciences, Inc. All applicants should be legally entitled to work for any employer in the U.S. For more information, please visit www.jouncetx.com.
- Website
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http://www.jouncetx.com
External link for Jounce Therapeutics, Inc.
- Industry
- Biotechnology Research
- Company size
- 51-200 employees
- Headquarters
- Cambridge, MA
- Type
- Public Company
- Founded
- 2013
- Specialties
- Cancer Immunotherapy, Immunology, Oncology, and Antibody Development
Locations
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Primary
780 Memorial Drive
Cambridge, MA 02139, US
Employees at Jounce Therapeutics, Inc.
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Robert Kamen
Advisory Partner at Third Rock Ventures
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Vikki Spaulding
Scientist
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Kristen Leone
Flow Cytometry Core Manager at Jounce Therapeutics, Inc.
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Kashonda Mann
“Service is the rent we pay for being. It is the very purpose of life, and not something you do in your spare time.” ~ Marian Wright Edelman