Ed Groleau

Continuous manufacturing, whether of the active pharmaceutical ingredient or drug product, continues to make inroads as companies advance select projects. https://lnkd.in/g7yhhGkp #pharma #biotech #innovation #continuousmanufacturing #ATMP

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#News: Eli Lilly and Company announced Friday that it is investing an additional $5.3 billion in its manufacturing site in #Indiana to boost the capacity for producing #tirzepatide, the active ingredient for the #blockbusterdrugs #Mounjaro and #Zepbound. Lilly said the funds will more than double its investment in a production site in Lebanon, Indiana. The pharma giant was initially going to invest $3.7 billion in April, but Lilly’s latest announcement will now bring the total to $9 billion. The investment aims to enhance the company’s capacity to manufacture the active pharmaceutical ingredient (API) for the wildly popular Mounjaro and Zepbound medications. “Today’s announcement tops the largest manufacturing investment in our company’s history and, we believe, represents the single largest investment in synthetic medicine API manufacturing in U.S. history,” said Lilly CEO David Ricks in a statement. “This multi-site campus will make our latest medicines, including Zepbound and Mounjaro, support pipeline growth and leverage the latest technology and automation for maximum efficiency, safety and quality control.” The Lebanon site plans to add around 200 jobs, mainly in engineering, operating personnel and lab technicians, bringing the total headcount to an estimated 900. Read more from.BioSpace 👇🏽 https://lnkd.in/eM8KT3kg

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Strategic sourcing goes beyond just price! Building strong, collaborative relationships with suppliers through effective #SRM unlocks a wealth of benefits: Cost savings beyond initial negotiation Streamlined processes & reduced workload Supplier accountability & focus on value delivery Competitive advantage through strategic partnerships Invest in your supplier network - it's a win-win! #Procurement #SupplyChainManagement

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Micro masters is highly recommended for anyone working in Supply Chain

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Check out our latest video on everything that's happening at ECS Botanics Holdings Ltd

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Check out APQC's latest research on trends and challenges in supply chains. These findings align well with what I'm seeing in the biotech industry this year. Companies are focusing on cleaner data and better analytics, supply chain orchestration through E2E supply chain management, and demand planning and S&OP. What's your strategic focus this year? Top Trends: Big data and analytics, supply chain digitization, enhanced data management. Key Obstacles: Tech implementation issues, collaboration gaps, data governance problems, labor shortages. Strategic Focus: Adaptability, flexibility and tech investments to stay competitive. https://lnkd.in/gdvewEKn #SupplyChain #BigData #AI #APQC #2024Trends #DataManagement

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Throughout my career, I’ve come to realize the immense value of having a mentor. This realization didn't come overnight; it was a journey that transformed the way I approach my professional life. Working with GEP, I was navigating a complex project that required strategic sourcing and supplier management at a scale I hadn’t dealt with before. Despite my skills and experience, I felt overwhelmed and unsure about certain decisions. That's when I decided to seek guidance from a senior colleague who had years of experience in the field. My mentor, Robert Bennett, not only provided me with invaluable insights but also shared his own experiences—both successes and failures. One particular instance stands out: I was negotiating a crucial contract with a major supplier. He guided me through the nuances of the negotiation process, helping me understand the importance of building a long-term relationship rather than focusing solely on immediate gains. His advice led to a successful agreement that benefitted both parties and strengthened our business relationship. But it wasn’t just about the technical guidance. Rob also encouraged me to develop my leadership skills, push beyond my comfort zone, and continuously seek knowledge. His mentorship taught me the importance of continuous learning and personal growth, which has since become a cornerstone of my professional philosophy. Now, as I step into my new role as the Sourcing & Contracting Manager, I carry forward the lessons I've learned from him. I strive to not only apply these insights to my work but also to mentor others, sharing the knowledge and experience I’ve gained. Mentorship is not just about having someone to turn to for advice. It’s about building a relationship that fosters growth, learning, and development. It’s about having someone who believes in your potential and challenges you to achieve more than you ever thought possible. So, if you’re navigating your career and feeling uncertain, I highly recommend finding a mentor. The guidance, support, and inspiration you receive can make all the difference. #Mentorship #ProfessionalGrowth #ContinuousLearning #Leadership

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Product-Packaging Stability Modeling Are you determining the shelf life of a product or designing a container closure system (CCS) to ensure the product achieves its desired shelf life? Traditionally, shelf life determination involves placing the product in various CCS configurations, periodically testing its stability, and recording the duration for which it meets the required criteria. This classical approach is both time-consuming and costly. If the product fails, the stability study must be repeated, further extending timelines and increasing expenses. Although this traditional method is no longer the industry standard, many companies still rely on it. Why is that? Often, senior management still insists on the outdated mentality of “Just put the product in a package!” In contrast, designing a CCS requires a thorough understanding of product kinetics, packaging barrier properties, and environmental conditions. This allows for an estimation of product stability using fundamental principles.  For detailed information, please visit my blog at https://lnkd.in/grgD4Mag.

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To drive better and faster business decisions, companies are working to enhance cross-functional collaboration and Supply Chain visibility. A refined Sales and Operations Planning (S&OP) process is key in achieving these goals. For insight on how to improve the S&OP process, check out Patrick Bower's article "How to Make S&OP Truly Strategic". Key takeaways include: - Balance Strategy and Tactics: Know the difference. Both are essential in business and S&OP. - Engage Executives Meaningfully: Ensure executive participation by focusing on strategic discussion and decision making in executive S&OP. - Identify Strategic Goals: Use internal meetings and public information to determine key initiatives. Update meeting content as goals and strategy shift. - Align Metrics and Discussions: Focus on metrics that reflect strategic goals, shifting from operational metrics to those with strategic implications. - Embrace Continuous Improvement: Regularly review and refine the S&OP process to stay aligned with evolving strategies. #BusinessStrategy #SupplyChainManagement #SOP #Collaboration #ContinuousImprovement #ASCM

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Supply Chain Risk Management can be challenging, but using established tools and strategies lets you focus your efforts where they can do the most good!

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Axcend: Making HPLC easy

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What an example of how critical financial stability is and its connection to supply chain disruptions. 💨 Akorns' recent shutdown has intensified the ongoing liquid albuterol shortage, critically impacting pediatric hospitals that rely on this medication amidst increasing asthma rates. The American Society of Hospital Pharmacists (ASHP) noted nine shortages in albuterol inhalation solutions, mainly due to Akorn's closure and Nephron supply issues. Albuterol is essential for treating asthma, affecting approximately 25 million Americans, with rising asthma rates. Studies highlight that toxic chemical exposure from gas stoves and urban air pollution significantly contribute to asthma cases, pushing for regulatory actions. Pediatric hospitals, already strained by recent surges in COVID, influenza, and RSV, now face the challenge of finding alternative treatments for albuterol. While some manufacturers like Mylan and Nephron are expected to resume supplies soon, the shortages have emphasized the need for improved pharmaceutical supply chain management to prevent future disruptions. This situation is important because it highlights the critical need for robust supply chains in healthcare to ensure the availability of essential medications, especially as environmental factors contribute to higher asthma incidences.

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ISM-Charlotte, Inc. ISM-CV Triangle Chapter ISM-CV Triad Chapter here is yet one more benefit of your membership- helping you negotiate your own compensation

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One reason I love working in employee communications is because I believe communications play a critical role in determining how effective any business strategy, and ultimately an organization can be. I have been working for the past three years to help build engagement at manufacturing sites with thousands of employees, connecting the dots between our company purpose, business results, and what employees do each day.   Employees who are not able to access computers or mobile devices very often, because they are on the production floor, have told me in focus groups that they prefer to receive information from their direct manager. I recently attended a Ragan Communications and PR Daily Employee Communications and Culture Conference in Chicago, and I knew I wanted to hear from experts about how they support managers to be effective communicators, particularly when their teams spend very little time online. I found all of the conference topics valuable and would highly recommend Ragan events. I left inspired and with my mind full of ideas. I wanted to share some of my key takeaways and highlights and thank people who made this such a great experience. Anne DeAngelis, Karen C. Forté, and Adrienne Leigh Hoyt provided practical advice along with data that confirms managers play a crucial role in engagement and that many managers are struggling. For example, they shared that Gallup found managers account for 70% of the variance in team engagement. They also grabbed my attention with these Zeno Group survey results from 2023 of middle managers in the U.S that found:  ·    78% are overwhelmed  ·    86% believe clear and timely communication is vital to their success  ·    Only 43% feel supported by their senior leaders   Besides manager communications, some other top sessions for me included a panel discussion with Jennifer George, Hillary U, Galit Mendelson, and Evan Helmlinger, covering best practices for communicating with deskless and dispersed workforces, and Tricia Taylor's advice regarding effective change communications in uncertain times.   Last but certainly not least, I was happy to enrich my network and be able to learn from and meet so many great comms professionals including Andres Muñiz, Teri Levy, Laura Probst, Mallary Becker, Amy Heisler, Meara Murphy, and Rachel Goff, while enjoying art, architecture, and springtime in Chicago. #employeecommunications #employeeengagement #internalcommunications #desklessworkforce #raganevents #managercommunications

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Recently, Alcami Corporation CEO William Humphries sat down with Pharmaceutical Technology to highlight the benefits of working with Alcami. Watch the full video to learn more about: 🔷How Alcami stays ahead of the curve and makes the smart investments in capacity and technology to meet market demand and address sector challenges. 🔷Understand Alcami's position to support the future of pharma and biotech, ready with innovative solutions and strategic partnerships that streamline and optimize the path to patients for clients’ therapeutics. 🔷Whether clients tap Alcami for one service or seek the benefit of a seamless end-to-end solution, the company’s Lab Services, Drug Product Manufacturing, and Pharma Storage and Services are fully integrated and optimized. Watch here➡️ https://lnkd.in/g7HmKBTw

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In honor of #InternationalClinicalTrialsDay, we salute the dedication of researchers, healthcare professionals, and patients who participate in clinical trials. Their commitment to advancing science and improving patient outcomes is inspiring! At #IllingworthResearchGroup, we are driven by a mission to make a difference every day and bring treatments to those in need, impacting patients' lives everywhere. #ClinicalTrialsDay #ClinicalResearch #ClinicalCareers

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What does #transformation look like, and how exactly are you rethinking your #supplychain in today’s landscape to ensure long-term success? https://lnkd.in/edfTwguN

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