Suzanne Jasberg
Minneapolis, Minnesota, United States
791 followers
500+ connections
About
Activity
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**This Father's Day, let's shine a light on the mental health struggles that many fathers face. Research shows that 10% of fathers experience…
**This Father's Day, let's shine a light on the mental health struggles that many fathers face. Research shows that 10% of fathers experience…
Liked by Suzanne Jasberg
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This Mother’s Day, take a few minutes to advocate for mothers by supporting crucial legislation aimed at improving maternal mental health. Perinatal…
This Mother’s Day, take a few minutes to advocate for mothers by supporting crucial legislation aimed at improving maternal mental health. Perinatal…
Liked by Suzanne Jasberg
Experience & Education
Licenses & Certifications
Publications
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The Clinical Impact of Neuroimaging in First-Episode Psychosis
Clinical Schizophrenia & Related Psychoses
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Seizure Induced by Deep Transcranial Magnetic Stimulation in an Adolescent with Depression
J Child Adolesc Psychopharmacol
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Schizophrenia During Menopausal Transition
Mental Health in Family Medicine
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Multifunctional prenylated peptides for live cell analysis.
Journal of the American Chemical Society
Protein prenylation is a common post-translational modification present in eukaryotic cells. Many key proteins involved in signal transduction pathways are prenylated, and inhibition of prenylation can be useful as a therapeutic intervention. While significant progress has been made in understanding protein prenylation in vitro, we have been interested in studying this process in living cells, including the question of where prenylated molecules localize. Here, we describe the synthesis and…
Protein prenylation is a common post-translational modification present in eukaryotic cells. Many key proteins involved in signal transduction pathways are prenylated, and inhibition of prenylation can be useful as a therapeutic intervention. While significant progress has been made in understanding protein prenylation in vitro, we have been interested in studying this process in living cells, including the question of where prenylated molecules localize. Here, we describe the synthesis and live cell analysis of a series of fluorescently labeled multifunctional peptides, based on the C-terminus of the naturally prenylated protein CDC42. A synthetic route was developed that features a key Acm to Scm protecting group conversion. This strategy was compatible with acid-sensitive isoprenoid moieties and allowed incorporation of an appropriate fluorophore as well as a cell-penetrating sequence (penetratin). These peptides are able to enter cells through different mechanisms, depending on the presence or absence of the penetratin vehicle and the nature of the prenyl group attached. Interestingly, prenylated peptides lacking penetratin are able to enter cells freely through an energy-independent process and localize in a perinuclear fashion. This effect extends to a prenylated peptide that includes a full "CAAX box" sequence (specifically, CVLL). Hence, these peptides open the door for studies of protein prenylation in living cells, including enzymatic processing and intracellular peptide trafficking. Moreover, the synthetic strategy developed here should be useful for the assembly of other types of peptides that contain acid-sensitive functionalities.
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Early Stage Schizophrenia: Assessment and Treatment
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Gabbard's Treatments of Psychiatric Disorders
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Neuroimaging and Other Neuroscience Measures
Schizophrenia and Related Disorders Primer, Oxford University Press
Neuroimaging and Other Neuroscience Measures
Other authors
Projects
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Investigation of the Relationship Between Cognition and Anatomical Networks in Schizophrenia
Poster presentation: acceptance: Schizophrenia International Research Society: April 2014
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A Pilot Study of Best Practices Using Imaging in New-Onset Psychosis
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Poster presentation at 2013 International Congress on Schizophrenia Research.
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EARLY STAGE SCHIZOPHRENIA: ASSESSMENT AND TREATMENT
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Early Stage Schizophrenia: Assessment and Treatment chapter in the next edition of Gabbard's Treatments of Psychiatric Disorders.
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Research Fellowship
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Research fellowship, focusing on neuroimaging, cognitive remediation and transcranial direct current stimulation.
Honors & Awards
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MSP Top Doctor Rising Star
MSP Magazine
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MN Monthly Top Doctor
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MSP Top Doctor Rising Star 2022
MSP Magazine
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MN Monthly Top Doctor 2022
Minnesota Monthly Magazine
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MSP Top Doctor Rising Star 2021
MSP Magazine
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Minnesota Psychiatric Society 2019 Psychiatrist of the Year
Minnesota Psychiatric Society
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MN Monthly Top Doctor 2018
Minnesota Monthly
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APA Research Colloquium for Junior Investigators Awardee
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Certificate of Recognition: for providing excellent patient-centered care and contributing to a culture of safety in the clinic
CMO University of Minnesota, M Health
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Lawn Fellowship
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First Episode Psychosis Fellow 2013-2014
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Wallace D Armstrong Award
University of Minnesota
Awarded to the medical student with the highest scholastic standing in biochemistry.
Organizations
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Clinical TMS society
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American Psychological Association
Member
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Phi Kappa Phi
Member
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Clinical TMS Society
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More activity by Suzanne
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This is what happens when you build a team positively for decades. Pictured here with one of Americas major hair loss experts ( aka Queen) Dr.…
This is what happens when you build a team positively for decades. Pictured here with one of Americas major hair loss experts ( aka Queen) Dr.…
Liked by Suzanne Jasberg
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This Mother’s Day, take a few minutes to advocate for mothers by supporting crucial legislation aimed at improving maternal mental health. The…
This Mother’s Day, take a few minutes to advocate for mothers by supporting crucial legislation aimed at improving maternal mental health. The…
Liked by Suzanne Jasberg
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The Perinatal Mental Health team at PrairieCare has introduced a bill in both the Minnesota House and Senate that requires payers to mandate and…
The Perinatal Mental Health team at PrairieCare has introduced a bill in both the Minnesota House and Senate that requires payers to mandate and…
Liked by Suzanne Jasberg
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Meeting cosmetic dermatologists from around the world is one of the best parts of being the Cosmetic Lead for the University of Minnesota. I am…
Meeting cosmetic dermatologists from around the world is one of the best parts of being the Cosmetic Lead for the University of Minnesota. I am…
Liked by Suzanne Jasberg
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We had a great time! (The irony about posting on social media about a talk regarding the risks of social media exposure)! 😋
We had a great time! (The irony about posting on social media about a talk regarding the risks of social media exposure)! 😋
Liked by Suzanne Jasberg
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I’m proud of my friend Paula DeSanto and her innovative team for opening Minnesota’s first safe injection site + drug use resource hub. Their hard…
I’m proud of my friend Paula DeSanto and her innovative team for opening Minnesota’s first safe injection site + drug use resource hub. Their hard…
Liked by Suzanne Jasberg
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Wishing a heartfelt Happy Physicians Week to my amazing colleagues. Your unwavering commitment to enhancing patient lives through expertise…
Wishing a heartfelt Happy Physicians Week to my amazing colleagues. Your unwavering commitment to enhancing patient lives through expertise…
Liked by Suzanne Jasberg
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What single word best captures the impact of female friendships in your professional journey? I choose 'Transformative'. Comment with your impactful…
What single word best captures the impact of female friendships in your professional journey? I choose 'Transformative'. Comment with your impactful…
Shared by Suzanne Jasberg
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I am so humbled to have presented at the academy with my collegies on social media and hair loss. Thank you Kaitlyn Bader for interviewing me…
I am so humbled to have presented at the academy with my collegies on social media and hair loss. Thank you Kaitlyn Bader for interviewing me…
Liked by Suzanne Jasberg
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